Pathways to Genome-targeted Therapies in Serous Ovarian Cancer

Joshua Axelrod, Joe Delaney

Division of Gynecologic Oncology, Department of Reproductive Medicine UCSD School of Medicine and UCSD Moores Cancer Center, 3855 Health Sciences Drive, La Jolla, CA 39216, USA

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Genome sequencing technologies and corresponding oncology publications have generated enormous publicly available datasets for many cancer types.  While this has enabled new treatments, and in some limited cases lifetime management of the disease, the treatment options for serous ovarian cancer remain dismal.  This review summarizes recent advances in our understanding of ovarian cancer, with a focus on heterogeneity, functional genomics, and actionable data. Journal of Nature and Science (JNSCI), 3(7):e408, 2017

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